Wednesday 14 October
8:30-8:55
Plenary session V: Capacity development in sub-Saharan Africa
Chair Prof. Tumani Corrah
Plenary session: Dr Michael Makanga
Challenges of capacity development in sub-Saharan Africa: EDCTP strategy (20 minutes talk, 5 minutes questions)
8:55-9:00 Transfer to parallel sessions
9:00-10:20
Parallel sessions: Clinical Trials research findings in sub-Saharan Africa and Scientific Presentations by EDCTP Fellows
HIV/AIDS
Chairs Prof. Nkandu P. Luo and Dr Abraham Alabi
9:00-9:05 Brief introduction from the Chairs
9:05-9:20 Bahati Andrew & Justine Bukenya: Prevalence of intra-vaginal practices in EDCTP cohorts in Uganda and
Tanzania & Sexual risk behaviour and risk perception among female sex workers enrolled in a microbicide
feasibility study in Kampala, Uganda
9:20-9:35 Papa Gallo Sow: Perceptions and practices regarding microbicides. A baseline survey of the social health
institute of Dakar
9:35-9:50 Suzan Nakate: Barriers to adherence to clinical appointments in a free Urban HIV care facility. A case of the
Infectious Diseases Institute Kampala, Uganda
9:50-10:05 Jean Nachega: The effect of pregnancy on adherence to highly active antiretroviral therapy among HIV-
infected South African women: A pharmacy claims-based analysis
10:05-10:20 Mariam A Adetunji: Risk of coronary heart disease based on ratio of total cholesterol to high density
lipoprotein in HIV infected ARV naïve patients
Malaria
Chairs Dr Andrew Kitua and Dr Klaus Winkel
9:00-9:05 Brief introduction from the Chairs
9:05-9:20 Davis Nwakanma: Application of real-time quantitative polymerase chain reaction 'opcr' in anti-malarial drug
trial
9:20-9:35 Alexis Nzila: In-vitro chemosensitization of antimalarials by verapamil and probenecid in Plasmodium
falciparum
9:35-9:50 Leah Mwai: Towards understanding the mechanisms of lumefantrine resistance.
9:50-10:05 Takafira Muduluza: Cytokine gene polymorphism analysis in children exposed to malaria and/or helminths
infections in Zimbabwe
10:05-10:20 Ayola Akim Adegnika: Ascaris lubriciodes as a risk factor for P. falciparum malaria infection during
pregnancy in Lambaréné, Gabon
Tuberculosis
Chairs Dr Veronique N. Penlap and Prof. Martin Grobusch
9:00-9:05 Brief introduction from the Chairs
9:05-9:20 Gibson Kibiki: New drugs against tuberculosis: Problems, progress, and evaluation of agents in clinical
development
9:20-9:35 Yusuf Mohammed: Response to treatment in sputum smear positive pulmonary tuberculosis patients in
relation to human immunodeficiency virus in Kano, Nigeria.
9:35-9:50 Sven Friedrich: Comparison of smear microscopy, solid culture and liquid culture for monitoring treatment
response in pulmonary tuberculosis
9:50-10:05 Bernd Eisele: Induction of antigen specific multifunctional T cells after vaccination with the live recombinant
tuberculosis vaccine VPM1002 in a Phase I clinical trial
10:05-10:20 Jan Verschoor: Mycolic acid antibody real-time inhibition test demonstrates that anti-mycolic acid antibodies
are surrogate markers for active tuberculosis
10:20-10:50 Coffee/Tea Break
10:50-12:00
Parallel sessions: Clinical Trials research findings in sub-Saharan Africa and Scientific Presentations by EDCTP Fellows continues
HIV/AIDS
Chairs Prof. Nkandu P. Luo and Dr Abraham Alabi
10:50-11:05 Louis-Marie Yindom: Hla alleles and kir genes frequencies in HIV-2 infected individuals from two cohorts in
West Africa
11:05-11:20 Mattia Prosperi: Prediction of antiretroviral therapy outcomes in poor resource countries: Comparison
between genotype resistance testing based versus treatment history models
11:20-11:35 Sabina Mugusi: The effect of rifampicin on clinical outcomes in patients treated with efavirenz containing
HAART.
11:35-11:50 Joseph Vyankandondera: Prevalence of HPV and association with other STIs among High-Risk women in
Kigali, Rwanda
11:50-12:00 Discussion
Malaria
Chairs Dr Andrew Kitua and Dr Klaus Winkel
10:50-11:05 Daniel Dodoo: The Afro-immuno assay multi-centre network project and capacity building for malaria
vaccine development in Africa
11:05-11:20 Aïssatou Toure: The ADRB assay: a new tool, correlated with clinical protection from Plasmodium
falciparum malaria, to test malaria vaccine
11:20-11:35 Charles Arama: Decreased percentage of plasmacytoid dendritic cells and increased plasma levels of
interferon alpha in Fulani children undergoing Plasmodium falciparum infection in Mali.
11:35-11:50 Victor Chalwe: HIV-1 infection increases the risk of severe malaria in semi-immune adults in Zambia
11:50-12:00 Discussion
Tuberculosis
Chairs Dr Veronique N. Penlap and Prof. Martin Grobusch
10:50-11:05 Hulda Swai: Novel approach to address the tuberculosis treatment regime
11:05-11:20 Agatha Ani: Dominant Mycobacterium tuberculosis genotypes in Nigeria
11:20-11:35 Sayoki G Mfinanga: Estimates of genetic variability of M. tuberculosis complex and its association with drug
resistance and treatment outcomes in Tanzania.
11:35-11:50 Kebba Touray: Spatial analysis of tuberculosis in an urban West African setting: Is there evidence of
clustering?
11:50-12:00 Discussion
12:00-13:00 Electronic and paper poster presentations
13:00-14:00 Lunch
14:00-15:35
Plenary session VI: EDCTP and Global Partnerships
Chairs: Dr Michael Makanga/Dr Dirk van der Roost
14:00-14:05 Brief introduction from the Chairs
14:05-14:15 The AAVP and UVRI model: Building research capacity through partnerships in synergy with
EDCTP
14:15-14:25 IPM: International Partnership for Microbicides
14:25-14:35 Wellcome Trust
14:35-14:45 Bill and Melinda Gates Foundation
14:45-14:55 ESSENCE: Enhancing Support for Strengthening the Effectiveness of National Capacity Effort
14:55-15:05 AMANET: African Malaria Network Trust
15:05-15:15 EMVI: European Malaria Vaccine Initiative
15:15-15:25 MMV: Medicines for Malaria Venture
15:25-15:35 Aeras Global TB Vaccine Foundation
15:35-16:00 Tea/Coffee break
16:00-17:30
Closing plenary session VII: EDCTP future perspectives
Chairs: Prof. David Ofori-Adjei and Dr Christian Burri
16:00-16:45: Dr Sodiomon Sirima / Prof. Charles Mgone–EDCTP: one world, one partnership
Forum recommendations and EDCTP–future research direction including new developments such a health
services research.
16:45-17:00: Award giving ceremony for outstanding African scientists
17:00-17:15: Dr Ruxandra Draghia-Akli, The Director of Health, European Commission
Future EDCTP perspective from the European Commission and Concluding Remarks
19:00-20.30 Closing dinner and award giving ceremony for young future scientists:
Essay competition winners